Degenerative Spinal Disorders

Our research on degenerative spinal disorders focuses predominantly on degenerative disease of the lumbar spine including spondylolisthesis, disc degeneration, and lumbar spinal stenosis. Our approach to researching these conditions is by patient-orientated research which refers to research that focuses on the patient, their caregivers, and families as engaged partners in the research process.  This research is then integrated into the health care system and clinical practice.  

We are currently conducting several randomized controlled trials on these conditions, and we are also conducting registry/large database research in collaboration with the Canadian Spine Outcomes Research Network.  In one current study we are optimizing patient-rated outcomes by determining the importance of pelvic parameters and sagittal balance on the surgical treatment of lumbar degenerative spondylolisthesis.  Our research on degenerative spinal disorders has been featured at major national and international spine meetings.  In our study published in CMAJ open we showed that patients with spinal stenosis awaiting spinal surgery experience deterioration in health-related quality of life irrespective of wait time, and that longer waits were associated with a delay in recovery during the first year after surgery.

Current Projects

  • The effect of prolonged post-operative antibiotic administration on the rate of infection in patients undergoing posterior spine surgery requiring a hemovac drain 
  • Fitbit pilot study to increase physical activity and overall health in post-operative lumbar degenerative spinal stenosis patients
  • Surgery vs. standardized non-operative care for the treatment of lumbar disc herniation: a Canadian trial
  • The natural history of degenerative lumbar spinal stenosis for patients on the surgical waiting list 
  • Clinical outcomes for interbody versus instrumented postolateral fusion following decompression for lumbar spinal stenosis with degenerative spondylolisthesis
  • Canadian Spine Outcomes Research Network
  • Decompression alone vs. Decompression and instrumented fusion for the management of lumbar spinal stenosis associated with stable degenerative spondylolisthesis: a pragmatic randomized clinical pilot trial
  • Importance of pelvic parameters and sagittal balance on the surgical treatment of lumbar degenerative spondylolisthesis

Select Publications

Urquhart JC, Alnaghmoosh N, Gurr KR, Bailey SI, Tallon C, Dehens S, Rosas Arellano MP, Bailey CS Posterolateral Versus Posterior Interbody Fusion in Lumbar Degenerative Spondylolisthesis. Clin Spine Surg. 2018 Nov;31(9):E446-E452. doi: 10.1097/BSD.0000000000000698.

Staudt MD, Bailey CS, Siddiqi F. Charcot spinal arthropathy in patients with congenital insensitivity to pain: a report of two cases and review of the literature.  Neurosurg Rev. 2018 Oct;41(4):899-908. 

Cushnie D, Johnstone R, Urquhart JC, Gurr KR, Bailey SI, Bailey CS. Quality of life and slip progression in degenerative spondylolisthesis treated non-operatively. Spine 15:E574-579 May 2018.

Radovanovic I, Urquhart JC, Gananapathy, Siddiqi F, Gurr KR, Bailey SI, Bailey CS. The influence of sagittal balance and spinopelvic parameters on the outcome of patients treated surgically with degenerative lumbar spinal stenosis. Journal of Neurosurgery: Spine 26:448-453, April 2017.

Rasoulinejad P, Urquhart J, Bailey CS. Current management of symptomatic lumbar disc herniations. Journal of Current Clinical Care 7:21-36, January 2017.

Bailey CS, Gurr KR, Bailey SI, Taylor D, Rosa-Arellano P, Urquhart, JC. Does the wait for lumbar degenerative spinal stenosis surgery had detrimental a effect on patient outcomes? A prospective observational study.  CMAJ OPEN 4:E185-E193, January 2016.